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220 Publikationen
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Brachtl G.
Differential Bone Marrow Homing Capacity of VLA-4 and CD38 High Expressing Chronic Lymphocytic Leukemia Cells
Brachtl G, Sahakyan K, Denk U, Girbl T, Alinger B, Hofbauer SW, Neureiter D, Hofbauer JP, Egle A, Greil R, Hartmann TN.
PLoS One. 2011;6(8):e23758. Epub 2011 Aug 18.
18.08.2011
Modifying Akt signaling in B-cell chronic lymphocytic leukemia cells.
Hofbauer SW, Piñón JD, Brachtl G, Haginger L, Wang W, Jöhrer K, Tinhofer I, Hartmann TN, and Greil R.
Cancer Research. 2010 Sep 7. [Epub ahead of print]
2010
Egle A.
Lysine Residue at Position 22 of the AID Protein Regulates Its Class Switch Activity
Geisberger R, Huemer M, Gassner FJ, Zaborsky N, Egle A, Greil R.
PLoS ONE. 2012. 7(2): e30667.
20.02.2012
Differential Bone Marrow Homing Capacity of VLA-4 and CD38 High Expressing Chronic Lymphocytic Leukemia Cells
Brachtl G, Sahakyan K, Denk U, Girbl T, Alinger B, Hofbauer SW, Neureiter D, Hofbauer JP, Egle A, Greil R, Hartmann TN.
PLoS One. 2011;6(8):e23758. Epub 2011 Aug 18.
18.08.2011
Development of CLL in the TCL1 transgenic mouse model is associated with severe skewing of the T-cell compartment homologous to human CLL.
Hofbauer JP, Heyder C, Denk U, Kocher T, Holler C, Trapin D, Asslaber D, Tinhofer I, Greil R, Egle A.
Leukemia. 2011 May 24. [Epub ahead of print]
24.05.2011
Regulatory T cells predict the time to initial treatment in early stage chronic lymphocytic leukemia.
Weiss L, Melchardt T, Egle A, Grabmer C, Greil R, Tinhofer I.
Cancer. 2011 May 15;117(10):2163-9. doi: 10.1002/cncr.25752. Epub 2010 Nov 18
15.05.2011
Fludarabine modulates composition and function of the T cell pool in patients with chronic lymphocytic leukaemia.
Gassner FJ, Weiss L, Geisberger R, Hofbauer JP, Egle A, Hartmann TN, Greil R, Tinhofer I.
Cancer Immunol Immunother. 2011 Jan;60(1):75-85. Epub 2010 Sep 21.
01/2011
MicroRNAs as biomarkers for the diagnosis and prognosis of human cancer.
Asslaber D, Pinon Hofbauer J, Greil R, Egle A.
Journal of Nucleic Acids Investigations. 2010, Dec 1, 1(1): 76-80.
01.12.2010
microRNA-34a expression correlates with MDM2 SNP309 polymorphism and treatment-free survival in chronic lymphocytic leukemia.
Asslaber D, Piñón JD, Seyfried I, Desch P, Stöcher M, Tinhofer I, Egle A, Merkel O, Greil R.
Blood. 2010 May 27;115(21):4191-7. Epub 2010 Jan 20.
27.05.2010
Interdependent regulation of p53 and miR-34a in chronic lymphocytic leukemia.
Merkel O, Asslaber D, Piñón JD, Egle A, Greil R.
Cell Cycle. 2010 Jul 15;9(14):2764-8. Epub 2010 Jul 3.
2010
Riding the 2-edged sword.
Egle A.
Blood. 2010 Jun 3;115(22):4325-6. Comment.
2010
An uncommon cause of anaemia: Sheehan's syndrome.
Melchardt T, Namberger K, Weiss L, Egle A, Faber V, Greil R.
Wiener Klinische Wochenschrift. 2010 Dec 7.
2010
Apoptosis of leukocytes triggered by acute DNA damage promotes lymphoma formation.
Labi V, Erlacher M, Krumschnabel G, Manzl C, Tzankov A, Pinon J, Egle A, Villunger A.
Genes & Development. 2010 Aug 1;24(15):1602-7.
2010
PKCbeta is essential for the development of chronic lymphocytic leukemia in the TCL1 transgenic mouse model: validation of PKCbeta as a therapeutic target in chronic lymphocytic leukemia.
Holler C, Piñón JD, Denk U, Heyder C, Hofbauer S, Greil R, Egle A.
Blood. 2009 Mar 19;113(12):2791-4. Epub 2009 Jan 23.
2009
The molecular and cellular biology of chronic lymphocytic leukemia as the basis for novel therapeutic approaches.
Pleyer L, Egle A, Hartmann TN, Greil R.
Nature Clinical Practice Oncology. 2009 Jul;6(7):405-18. Epub 2009 Jun 2. Review.
2009
Novel therapeutics approaches to chronic lymphocytic leukemia based on recent biological insights.
Hartmann TN, Pleyer L, Desch P, Egle A, Greil R.
Discovering Medicine. 2009 Oct;8(42):157-64. Review.
2009
Bim and Bmf in tissue homeostasis and malignant disease.
Piñon JD, Labi V, Egle A, Villunger A.
Oncogene. 2008 Dec;27 Suppl 1:S41-52. Review.
2008
The effect of IgVH mutational status on the induction of apoptosis by rituximab in patients with heavily pretreated B-cell chronic lymphocytic leukemia: evidence from a clinical phase I/II trial.
Tinhofer I, Steurer M, Leitinger G, Rumpold H, Egle A, Erdel M, Greil R.
Haematologica-The Hematology Journal. 2006 Sep;91(9):1291-3.
2006
Expression levels of CD38 in T cells predict course of disease in male patients with B-chronic lymphocytic leukemia.
Tinhofer I, Rubenzer G, Holler C, Hofstaetter E, Stoecher M, Egle A, Steurer M, Greil R.
Blood. 2006 Nov 1;108(9):2950-6. Epub 2006 Jul 6.
2006
Analysis of Bcl-2 protein expression in chronic lymphocytic leukemia: a comparison of three semiquantitation techniques
Marschitz I, Tinhofer I, Hittmair A, Egle A, Kos M, Greil R
AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 113,219-229, 2000
2000
Expression of functional Interleukin-15 receptor and autocrine production of interleukin-15 as mechanisms of tumor propagation in multiple myeloma.
Tinhofer I, Marschitz I, Henn T, Egle A, Greil R
Blood, 2000 Jan 15;95(2):610-618.
2000
Differential sensitivity of CD4+ and CD8+ T lymphocytes to the killing efficacy of Fas(Apo-1/CD95) ligand+ tumor cells in B chronic lymphocytic leukemia.
Tinhofer I, Marschitz I, Egle A, Henn T, Villunger A, Greil R.
Blood. 1998 Jun 1;91(11):4273-81.
1998
IL-10 serum levels in B-cell chronic lymphocytic leukaemia.
Egle A, Marschitz I, Posch B, Herold M, Greil R.
Br J Haematol. 1996 Jul;94(1):211-2.
1996
Modulation of Apo-1/Fas (CD95)-induced programmed cell death in myeloma cells by interferon-alpha 2.
Egle A, Villunger A, Kos M, Böck G, Gruber J, Auer B, Greil R.
Eur J Immunol. 1996 Dec;26(12):3119-26.
1996
Lysine Residue at Position 22 of the AID Protein Regulates Its Class Switch Activity
Geisberger R, Huemer M, Gassner FJ, Zaborsky N, Egle A, Greil R.
PLoS ONE. 2012. 7(2): e30667.
20.02.2012
Differential Bone Marrow Homing Capacity of VLA-4 and CD38 High Expressing Chronic Lymphocytic Leukemia Cells
Brachtl G, Sahakyan K, Denk U, Girbl T, Alinger B, Hofbauer SW, Neureiter D, Hofbauer JP, Egle A, Greil R, Hartmann TN.
PLoS One. 2011;6(8):e23758. Epub 2011 Aug 18.
18.08.2011
Development of CLL in the TCL1 transgenic mouse model is associated with severe skewing of the T-cell compartment homologous to human CLL.
Hofbauer JP, Heyder C, Denk U, Kocher T, Holler C, Trapin D, Asslaber D, Tinhofer I, Greil R, Egle A.
Leukemia. 2011 May 24. [Epub ahead of print]
24.05.2011
Regulatory T cells predict the time to initial treatment in early stage chronic lymphocytic leukemia.
Weiss L, Melchardt T, Egle A, Grabmer C, Greil R, Tinhofer I.
Cancer. 2011 May 15;117(10):2163-9. doi: 10.1002/cncr.25752. Epub 2010 Nov 18
15.05.2011
Fludarabine modulates composition and function of the T cell pool in patients with chronic lymphocytic leukaemia.
Gassner FJ, Weiss L, Geisberger R, Hofbauer JP, Egle A, Hartmann TN, Greil R, Tinhofer I.
Cancer Immunol Immunother. 2011 Jan;60(1):75-85. Epub 2010 Sep 21.
01/2011
MicroRNAs as biomarkers for the diagnosis and prognosis of human cancer.
Asslaber D, Pinon Hofbauer J, Greil R, Egle A.
Journal of Nucleic Acids Investigations. 2010, Dec 1, 1(1): 76-80.
01.12.2010
microRNA-34a expression correlates with MDM2 SNP309 polymorphism and treatment-free survival in chronic lymphocytic leukemia.
Asslaber D, Piñón JD, Seyfried I, Desch P, Stöcher M, Tinhofer I, Egle A, Merkel O, Greil R.
Blood. 2010 May 27;115(21):4191-7. Epub 2010 Jan 20.
27.05.2010
Interdependent regulation of p53 and miR-34a in chronic lymphocytic leukemia.
Merkel O, Asslaber D, Piñón JD, Egle A, Greil R.
Cell Cycle. 2010 Jul 15;9(14):2764-8. Epub 2010 Jul 3.
2010
Riding the 2-edged sword.
Egle A.
Blood. 2010 Jun 3;115(22):4325-6. Comment.
2010
An uncommon cause of anaemia: Sheehan's syndrome.
Melchardt T, Namberger K, Weiss L, Egle A, Faber V, Greil R.
Wiener Klinische Wochenschrift. 2010 Dec 7.
2010
Apoptosis of leukocytes triggered by acute DNA damage promotes lymphoma formation.
Labi V, Erlacher M, Krumschnabel G, Manzl C, Tzankov A, Pinon J, Egle A, Villunger A.
Genes & Development. 2010 Aug 1;24(15):1602-7.
2010
PKCbeta is essential for the development of chronic lymphocytic leukemia in the TCL1 transgenic mouse model: validation of PKCbeta as a therapeutic target in chronic lymphocytic leukemia.
Holler C, Piñón JD, Denk U, Heyder C, Hofbauer S, Greil R, Egle A.
Blood. 2009 Mar 19;113(12):2791-4. Epub 2009 Jan 23.
2009
The molecular and cellular biology of chronic lymphocytic leukemia as the basis for novel therapeutic approaches.
Pleyer L, Egle A, Hartmann TN, Greil R.
Nature Clinical Practice Oncology. 2009 Jul;6(7):405-18. Epub 2009 Jun 2. Review.
2009
Novel therapeutics approaches to chronic lymphocytic leukemia based on recent biological insights.
Hartmann TN, Pleyer L, Desch P, Egle A, Greil R.
Discovering Medicine. 2009 Oct;8(42):157-64. Review.
2009
Bim and Bmf in tissue homeostasis and malignant disease.
Piñon JD, Labi V, Egle A, Villunger A.
Oncogene. 2008 Dec;27 Suppl 1:S41-52. Review.
2008
The effect of IgVH mutational status on the induction of apoptosis by rituximab in patients with heavily pretreated B-cell chronic lymphocytic leukemia: evidence from a clinical phase I/II trial.
Tinhofer I, Steurer M, Leitinger G, Rumpold H, Egle A, Erdel M, Greil R.
Haematologica-The Hematology Journal. 2006 Sep;91(9):1291-3.
2006
Expression levels of CD38 in T cells predict course of disease in male patients with B-chronic lymphocytic leukemia.
Tinhofer I, Rubenzer G, Holler C, Hofstaetter E, Stoecher M, Egle A, Steurer M, Greil R.
Blood. 2006 Nov 1;108(9):2950-6. Epub 2006 Jul 6.
2006
Analysis of Bcl-2 protein expression in chronic lymphocytic leukemia: a comparison of three semiquantitation techniques
Marschitz I, Tinhofer I, Hittmair A, Egle A, Kos M, Greil R
AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 113,219-229, 2000
2000
Expression of functional Interleukin-15 receptor and autocrine production of interleukin-15 as mechanisms of tumor propagation in multiple myeloma.
Tinhofer I, Marschitz I, Henn T, Egle A, Greil R
Blood, 2000 Jan 15;95(2):610-618.
2000
Differential sensitivity of CD4+ and CD8+ T lymphocytes to the killing efficacy of Fas(Apo-1/CD95) ligand+ tumor cells in B chronic lymphocytic leukemia.
Tinhofer I, Marschitz I, Egle A, Henn T, Villunger A, Greil R.
Blood. 1998 Jun 1;91(11):4273-81.
1998
IL-10 serum levels in B-cell chronic lymphocytic leukaemia.
Egle A, Marschitz I, Posch B, Herold M, Greil R.
Br J Haematol. 1996 Jul;94(1):211-2.
1996
Modulation of Apo-1/Fas (CD95)-induced programmed cell death in myeloma cells by interferon-alpha 2.
Egle A, Villunger A, Kos M, Böck G, Gruber J, Auer B, Greil R.
Eur J Immunol. 1996 Dec;26(12):3119-26.
1996
Faber V.
An uncommon cause of anaemia: Sheehan's syndrome.
Melchardt T, Namberger K, Weiss L, Egle A, Faber V, Greil R.
Wiener Klinische Wochenschrift. 2010 Dec 7.
2010
Geisberger R.
Lysine Residue at Position 22 of the AID Protein Regulates Its Class Switch Activity
Geisberger R, Huemer M, Gassner FJ, Zaborsky N, Egle A, Greil R.
PLoS ONE. 2012. 7(2): e30667.
20.02.2012
Fludarabine modulates composition and function of the T cell pool in patients with chronic lymphocytic leukaemia.
Gassner FJ, Weiss L, Geisberger R, Hofbauer JP, Egle A, Hartmann TN, Greil R, Tinhofer I.
Cancer Immunol Immunother. 2011 Jan;60(1):75-85. Epub 2010 Sep 21.
01/2011
Lysine Residue at Position 22 of the AID Protein Regulates Its Class Switch Activity
Geisberger R, Huemer M, Gassner FJ, Zaborsky N, Egle A, Greil R.
PLoS ONE. 2012. 7(2): e30667.
20.02.2012
Fludarabine modulates composition and function of the T cell pool in patients with chronic lymphocytic leukaemia.
Gassner FJ, Weiss L, Geisberger R, Hofbauer JP, Egle A, Hartmann TN, Greil R, Tinhofer I.
Cancer Immunol Immunother. 2011 Jan;60(1):75-85. Epub 2010 Sep 21.
01/2011
Greil R.
Canonical and Noncanonical Hedgehog/GLI Signaling in Hematological Malignancies.
Aberger F, Kern D, Greil R, Hartmann TN.
Vitamins & Hormones. 2012;88:25-54.
01.03.2012
Lysine Residue at Position 22 of the AID Protein Regulates Its Class Switch Activity
Geisberger R, Huemer M, Gassner FJ, Zaborsky N, Egle A, Greil R.
PLoS ONE. 2012. 7(2): e30667.
20.02.2012
Chemokine-dependent B cell-T cell interactions in chronic lymphocytic leukemia and multiple myeloma - targets for therapeutic intervention?
Jöhrer K, Hofbauer SW, Zelle-Rieser C, Greil R, Hartmann TN.
Expert Opinion on Biological Therapy. 2012 Feb 15.
15.02.2012
Antimyeloma activity of the sesquiterpene lactone cnicin: impact on Pim-2 kinase as a novel therapeutic target.
Jöhrer K, Obkircher M, Neureiter D, Parteli J, Zelle-Rieser C, Maizner E, Kern J, Hermann M, Hamacher F, Merkel O, Wacht N, Zidorn C, Scheideler M, Greil R.
Journal of Molecular Medicine-JMM. 2011 Dec 29.
29.12.2011
Differential Bone Marrow Homing Capacity of VLA-4 and CD38 High Expressing Chronic Lymphocytic Leukemia Cells
Brachtl G, Sahakyan K, Denk U, Girbl T, Alinger B, Hofbauer SW, Neureiter D, Hofbauer JP, Egle A, Greil R, Hartmann TN.
PLoS One. 2011;6(8):e23758. Epub 2011 Aug 18.
18.08.2011
Novel Therapeutic Options in Anaplastic Large Cell Lymphoma: Molecular Targets and Immunological Tools.
Merkel O, Hamacher F, Sifft E, Kenner L, Greil R; for the European Research Initiative on Anaplastic Large Cell Lymphoma.
Molecular Cancer Therapeutics. 2011 Jun 28.
28.06.2011
ASH Report. Novel agents in diffuse large B-cell lymphoma: A short update including ASH 2010.
Melchardt T, Hofbauer SW, Greil R, Hopfinger G.
Memo - Magazine of European Medical Oncology. 2011 June 1; 4(2): 120-123.
01.06.2011
Development of CLL in the TCL1 transgenic mouse model is associated with severe skewing of the T-cell compartment homologous to human CLL.
Hofbauer JP, Heyder C, Denk U, Kocher T, Holler C, Trapin D, Asslaber D, Tinhofer I, Greil R, Egle A.
Leukemia. 2011 May 24. [Epub ahead of print]
24.05.2011
Regulatory T cells predict the time to initial treatment in early stage chronic lymphocytic leukemia.
Weiss L, Melchardt T, Egle A, Grabmer C, Greil R, Tinhofer I.
Cancer. 2011 May 15;117(10):2163-9. doi: 10.1002/cncr.25752. Epub 2010 Nov 18
15.05.2011
Fludarabine modulates composition and function of the T cell pool in patients with chronic lymphocytic leukaemia.
Gassner FJ, Weiss L, Geisberger R, Hofbauer JP, Egle A, Hartmann TN, Greil R, Tinhofer I.
Cancer Immunol Immunother. 2011 Jan;60(1):75-85. Epub 2010 Sep 21.
01/2011
MicroRNAs as biomarkers for the diagnosis and prognosis of human cancer.
Asslaber D, Pinon Hofbauer J, Greil R, Egle A.
Journal of Nucleic Acids Investigations. 2010, Dec 1, 1(1): 76-80.
01.12.2010
Inhibition of GLI, but not Smoothened, induces apoptosis in chronic lymphocytic leukemia cells.
Desch P, Asslaber D, Kern D, Schnidar H, Mangelberger D, Alinger B, Stoecher M, Hofbauer SW, Neureiter D, Tinhofer I, Aberger F, Hartmann TN, Greil R.
Oncogene. 2010 Sep 2;29(35):4885-95. Epub 2010 Jul 5.
02.09.2010
microRNA-34a expression correlates with MDM2 SNP309 polymorphism and treatment-free survival in chronic lymphocytic leukemia.
Asslaber D, Piñón JD, Seyfried I, Desch P, Stöcher M, Tinhofer I, Egle A, Merkel O, Greil R.
Blood. 2010 May 27;115(21):4191-7. Epub 2010 Jan 20.
27.05.2010
Interdependent regulation of p53 and miR-34a in chronic lymphocytic leukemia.
Merkel O, Asslaber D, Piñón JD, Egle A, Greil R.
Cell Cycle. 2010 Jul 15;9(14):2764-8. Epub 2010 Jul 3.
2010
An uncommon cause of anaemia: Sheehan's syndrome.
Melchardt T, Namberger K, Weiss L, Egle A, Faber V, Greil R.
Wiener Klinische Wochenschrift. 2010 Dec 7.
2010
Modifying Akt signaling in B-cell chronic lymphocytic leukemia cells.
Hofbauer SW, Piñón JD, Brachtl G, Haginger L, Wang W, Jöhrer K, Tinhofer I, Hartmann TN, and Greil R.
Cancer Research. 2010 Sep 7. [Epub ahead of print]
2010
Identification of differential and functionally active miRNAs in both anaplastic lymphoma kinase (ALK)+ and ALK- anaplastic large-cell lymphoma.
Merkel O, Hamacher F, Laimer D, Sifft E, Trajanoski Z, Scheideler M, Egger G, Hassler MR, Thallinger C, Schmatz A, Turner SD, Greil R, Kenner L.
Proceedings of the National Academy of Sciences of the United States of America. 2010 Aug 30.
2010
Neue Therapie in Sicht.
Merkel O, Kenner L, Greil R
SpringerMedizin. 22.09.2010
2010
PKCbeta is essential for the development of chronic lymphocytic leukemia in the TCL1 transgenic mouse model: validation of PKCbeta as a therapeutic target in chronic lymphocytic leukemia.
Holler C, Piñón JD, Denk U, Heyder C, Hofbauer S, Greil R, Egle A.
Blood. 2009 Mar 19;113(12):2791-4. Epub 2009 Jan 23.
2009
Circulating B-cell chronic lymphocytic leukemia cells display impaired migration to lymphnodes and bone marrow.
Hartmann T, Grabovsky V, Wang W, Desch P, Rubenzer G, Wollner S, Binsky I, Vallon-Eberhard A, Sapoznikov A, Haran M, Shachar I, Burger M, Honczarenko M, Greil R, Alon R.
Cancer Research. 2009 Apr 1;69(7):3121-30. Epub 2009 Mar 17.
2009
The molecular and cellular biology of chronic lymphocytic leukemia as the basis for novel therapeutic approaches.
Pleyer L, Egle A, Hartmann TN, Greil R.
Nature Clinical Practice Oncology. 2009 Jul;6(7):405-18. Epub 2009 Jun 2. Review.
2009
Difference in the relative distribution of CD4+ T-cell subsets in B-CLL with mutated and unmutated immunoglobulin (Ig) VH genes: implication for the course of disease.
Tinhofer I, Weiss L, Gassner F, Rubenzer G, Holler C, Greil R.
Journal of Immunotherapy. 2009 Apr;32(3):302-9.
2009
Novel therapeutics approaches to chronic lymphocytic leukemia based on recent biological insights.
Hartmann TN, Pleyer L, Desch P, Egle A, Greil R.
Discovering Medicine. 2009 Oct;8(42):157-64. Review.
2009
SNP309 as predictor for sensitivity of CLL cells to the MDM2 inhibitor nutlin-3a.
Seyfried I, Hofbauer S, Stoecher M, Greil R, Tinhofer I.
Blood. 2008 Sep 1;112(5):2168; author reply 2169. No abstract available.
2008
MDM2 SNP309 is associated with poor outcome in B-cell chronic lymphocytic leukemia.
Gryshchenko I, Hofbauer S, Stoecher M, Daniel PT, Steurer M, Gaiger A, Eichenberger K, Greil R, Tinhofer I.
Journal of Clinical Oncology. 2008 May 10; 26(14):2252-7.
2008
Arsenic Trioxide induces apoptosis preferably in B-CLL cells of high risk patients including del17p13.
Merkel O, Heyder C, Asslaber D, Hamacher H, Holler C, Stöcher M, Tinhofer I, Greil R.
Journal of Molecular Medicine-JMM. 2008 May;86(5):541-52. Epub 2008 Feb 23.
2008
Tumour-immune cell interactions modulated by chemokines.
Jöhrer K, Pleyer L, Olivier A, Maizner E, Zelle-Rieser C, Greil R.
Expert Opinion on Biological Therapy. 2008 Mar;8(3):269-90. Review.
2008
The effect of IgVH mutational status on the induction of apoptosis by rituximab in patients with heavily pretreated B-cell chronic lymphocytic leukemia: evidence from a clinical phase I/II trial.
Tinhofer I, Steurer M, Leitinger G, Rumpold H, Egle A, Erdel M, Greil R.
Haematologica-The Hematology Journal. 2006 Sep;91(9):1291-3.
2006
Expression levels of CD38 in T cells predict course of disease in male patients with B-chronic lymphocytic leukemia.
Tinhofer I, Rubenzer G, Holler C, Hofstaetter E, Stoecher M, Egle A, Steurer M, Greil R.
Blood. 2006 Nov 1;108(9):2950-6. Epub 2006 Jul 6.
2006
IL-4 inhibits the TNF-alpha induced proliferation of renal cell carcinoma (RCC) and cooperates with TNF-alpha to induce apoptotic and cytokine responses by RCC: implications for antitumor immune responses.
Falkensammer C, Jöhrer K, Gander H, Ramoner R, Putz T, Rahm A, Greil R, Bartsch G, Thurnher M.
Cancer Immunology Immunotherapy. 2006 Oct;55(10):1228-37. Epub 2006 Jan 28.
2006
A role of TRAIL in killing osteoblasts by myeloma cells.
Tinhofer I, Biedermann R, Krismer M, Crazzolara R, Greil R.
FASEB Journal. 2006 Apr;20(6):759-61. Epub 2006 Jan 25.
2006
Polyacetylenes from the Apiaceae Vegetables Carrot, Celery, Fennel, Parsley, and Parsnip and Their Cytotoxic Activities.
Zidorn C, Johrer K, Ganzera M, Schubert B, Sigmund EM, Mader J, Greil R, Ellmerer EP, Stuppner H.
Journal of Agricultural and Food Chemistry. 2005 Apr 6;53(7):2518-2523.
2005
1,10-Epoxyhypocretenolides from the Azorean Endemic Leontodon rigens (Asteraceae)
Zidorn C, Ellmerer EP, Konwalinka G, Ongania KH, Schwaha R, Greil R, Jöhrer K, Perry NB, Stuppner H
Letters in Organic Chemistry. Volume 2, Number 5, August 2005 , pp. 461-464(4).
2005
Up-regulation of functional chemokine receptor CCR3 in human renal cell carcinoma.
Jöhrer K, Zelle-Rieser C, Perathoner A, Moser P, Hager M, Ramoner R, Gander H, Höltl L, Bartsch G, Greil R, Thurnher M.
Clinical Cancer Research. 2005 Apr 1;11(7):2459-65.
2005
Transendothelial migration of myeloma cells is increased by tumor necrosis factor (TNF)-alpha via TNF receptor 2 and autocrine up-regulation of MCP-1.
Jöhrer K, Janke K, Krugmann J, Fiegl M, Greil R.
Clinical Cancer Research. 2004 Mar 15;10(6):1901-10.
2004
Elevated levels of soluble CD44 are associated with advanced disease and in vitro proliferation of neoplastic lymphocytes in B-cell chronic lymphocytic leukaemia.
Eisterer W, Bechter O, Söderberg O, Nilsson K, Terol M, Greil R, Thaler J, Herold M, Finke L, Günthert U, Montserrat E, Stauder R.
Leukemia Research. 2004 Oct;28(10):1043-51.
2004
Tetrocarcin-A-induced ER stress mediates apoptosis in B-CLL cells via a Bcl-2--independent pathway.
Anether G, Tinhofer I, Senfter M, Greil R.
Blood. 2003 Jun 1;101(11):4561-8. Epub 2003 Jan 30.
2003
Tracking death dealing by Fas and TRAIL in lymphatic neoplastic disorders: pathways, targets, and therapeutic tools.
Greil R, Anether G, Johrer K, Tinhofer I.
Journal of Leukocyte Biology. 2003 Sep;74(3):311-30. Review.
2003
Tuning the rheostat of the myelopoietic system via Fas and TRAIL.
Greil R, Anether G, Johrer K, Tinhofer I.
Critical Reviews in Immunology. 2003;23(4):301-22. Review.
2003
Stressful death of T-ALL tumor cells after treatment with the anti-tumor agent Tetrocarcin-A.
Tinhofer I, Anether G, Senfter M, Pfaller K, Bernhard D, Hara M, Greil R.
FASEB J. 2002 Aug;16(10):1295-7. Epub 2002 Jun 7.
2002
Histone deacetylase inhibitors potently repress CXCR4 chemokine receptor expression and function in acute lymphoblastic leukaemia.
Crazzolara R, Jöhrer K, Johnstone RW, Greil R, Kofler R, Meister B, Bernhard D.
Br J Haematol. 2002 Dec;119(4):965-9.
2002
Interleukin-15 as a potential costimulatory cytokine in CD154 gene therapy of chronic lymphocytic leukemia.
Anether G, Marschitz I, Tinhofer I, Greil R.
Blood, 2002 Jan 15;99(2):722-3.
2002
Resveratrol, a tumor-suppressive compound from grapes, induces apoptosis via a novel mitochondrial pathway controlled by bcl-2.
Tinhofer I, Bernhard D, Senfter M, Anether G, Loeffler M, Kroemer G, Kofler R, Csordas A, Greil R
THE FASEB JOURNAL, 2001 Jul;15(9):1613-5
2001
Inhibition of histone deacetylase activity enhances Fas receptor-mediated apoptosis in leukemic lymphoblasts.
Bernhard D, Skvortsov S, Tinhofer I, Hübl H, Greil R, Csordas A, Kofler R.
Cell Death Differ. 2001 Oct;8(10):1014-21.
2001
Analysis of Bcl-2 protein expression in chronic lymphocytic leukemia: a comparison of three semiquantitation techniques
Marschitz I, Tinhofer I, Hittmair A, Egle A, Kos M, Greil R
AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 113,219-229, 2000
2000
Expression of functional Interleukin-15 receptor and autocrine production of interleukin-15 as mechanisms of tumor propagation in multiple myeloma.
Tinhofer I, Marschitz I, Henn T, Egle A, Greil R
Blood, 2000 Jan 15;95(2):610-618.
2000
Gastric cancer cell lines lack Fas Ligand (FasL) expression but kill T cells via a FasL-independent pathway.
Tinhofer I, Wykypiel H, Marschitz I, Henn T, Greil R.
GUT, 2000 May;46(5):738-740.
2000
Resveratrol causes arrest in the S-phase prior to Fas-independent apoptosis in CEM-C7H2 acute leukemia cells.
Bernhard D, Tinhofer I, Tonko M, Hübl H, Ausserlechner MJ, Greil R, Kofler R, Csordas A.
Cell Death Differ. 2000 Sep;7(9):834-42.
2000
Differential sensitivity of CD4+ and CD8+ T lymphocytes to the killing efficacy of Fas(Apo-1/CD95) ligand+ tumor cells in B chronic lymphocytic leukemia.
Tinhofer I, Marschitz I, Egle A, Henn T, Villunger A, Greil R.
Blood. 1998 Jun 1;91(11):4273-81.
1998
IL-10 serum levels in B-cell chronic lymphocytic leukaemia.
Egle A, Marschitz I, Posch B, Herold M, Greil R.
Br J Haematol. 1996 Jul;94(1):211-2.
1996
Modulation of Apo-1/Fas (CD95)-induced programmed cell death in myeloma cells by interferon-alpha 2.
Egle A, Villunger A, Kos M, Böck G, Gruber J, Auer B, Greil R.
Eur J Immunol. 1996 Dec;26(12):3119-26.
1996
Canonical and Noncanonical Hedgehog/GLI Signaling in Hematological Malignancies.
Aberger F, Kern D, Greil R, Hartmann TN.
Vitamins & Hormones. 2012;88:25-54.
01.03.2012
Lysine Residue at Position 22 of the AID Protein Regulates Its Class Switch Activity
Geisberger R, Huemer M, Gassner FJ, Zaborsky N, Egle A, Greil R.
PLoS ONE. 2012. 7(2): e30667.
20.02.2012
Chemokine-dependent B cell-T cell interactions in chronic lymphocytic leukemia and multiple myeloma - targets for therapeutic intervention?
Jöhrer K, Hofbauer SW, Zelle-Rieser C, Greil R, Hartmann TN.
Expert Opinion on Biological Therapy. 2012 Feb 15.
15.02.2012
Antimyeloma activity of the sesquiterpene lactone cnicin: impact on Pim-2 kinase as a novel therapeutic target.
Jöhrer K, Obkircher M, Neureiter D, Parteli J, Zelle-Rieser C, Maizner E, Kern J, Hermann M, Hamacher F, Merkel O, Wacht N, Zidorn C, Scheideler M, Greil R.
Journal of Molecular Medicine-JMM. 2011 Dec 29.
29.12.2011
Differential Bone Marrow Homing Capacity of VLA-4 and CD38 High Expressing Chronic Lymphocytic Leukemia Cells
Brachtl G, Sahakyan K, Denk U, Girbl T, Alinger B, Hofbauer SW, Neureiter D, Hofbauer JP, Egle A, Greil R, Hartmann TN.
PLoS One. 2011;6(8):e23758. Epub 2011 Aug 18.
18.08.2011
Novel Therapeutic Options in Anaplastic Large Cell Lymphoma: Molecular Targets and Immunological Tools.
Merkel O, Hamacher F, Sifft E, Kenner L, Greil R; for the European Research Initiative on Anaplastic Large Cell Lymphoma.
Molecular Cancer Therapeutics. 2011 Jun 28.
28.06.2011
ASH Report. Novel agents in diffuse large B-cell lymphoma: A short update including ASH 2010.
Melchardt T, Hofbauer SW, Greil R, Hopfinger G.
Memo - Magazine of European Medical Oncology. 2011 June 1; 4(2): 120-123.
01.06.2011
Development of CLL in the TCL1 transgenic mouse model is associated with severe skewing of the T-cell compartment homologous to human CLL.
Hofbauer JP, Heyder C, Denk U, Kocher T, Holler C, Trapin D, Asslaber D, Tinhofer I, Greil R, Egle A.
Leukemia. 2011 May 24. [Epub ahead of print]
24.05.2011
Regulatory T cells predict the time to initial treatment in early stage chronic lymphocytic leukemia.
Weiss L, Melchardt T, Egle A, Grabmer C, Greil R, Tinhofer I.
Cancer. 2011 May 15;117(10):2163-9. doi: 10.1002/cncr.25752. Epub 2010 Nov 18
15.05.2011
Fludarabine modulates composition and function of the T cell pool in patients with chronic lymphocytic leukaemia.
Gassner FJ, Weiss L, Geisberger R, Hofbauer JP, Egle A, Hartmann TN, Greil R, Tinhofer I.
Cancer Immunol Immunother. 2011 Jan;60(1):75-85. Epub 2010 Sep 21.
01/2011
MicroRNAs as biomarkers for the diagnosis and prognosis of human cancer.
Asslaber D, Pinon Hofbauer J, Greil R, Egle A.
Journal of Nucleic Acids Investigations. 2010, Dec 1, 1(1): 76-80.
01.12.2010
Inhibition of GLI, but not Smoothened, induces apoptosis in chronic lymphocytic leukemia cells.
Desch P, Asslaber D, Kern D, Schnidar H, Mangelberger D, Alinger B, Stoecher M, Hofbauer SW, Neureiter D, Tinhofer I, Aberger F, Hartmann TN, Greil R.
Oncogene. 2010 Sep 2;29(35):4885-95. Epub 2010 Jul 5.
02.09.2010
microRNA-34a expression correlates with MDM2 SNP309 polymorphism and treatment-free survival in chronic lymphocytic leukemia.
Asslaber D, Piñón JD, Seyfried I, Desch P, Stöcher M, Tinhofer I, Egle A, Merkel O, Greil R.
Blood. 2010 May 27;115(21):4191-7. Epub 2010 Jan 20.
27.05.2010
Interdependent regulation of p53 and miR-34a in chronic lymphocytic leukemia.
Merkel O, Asslaber D, Piñón JD, Egle A, Greil R.
Cell Cycle. 2010 Jul 15;9(14):2764-8. Epub 2010 Jul 3.
2010
An uncommon cause of anaemia: Sheehan's syndrome.
Melchardt T, Namberger K, Weiss L, Egle A, Faber V, Greil R.
Wiener Klinische Wochenschrift. 2010 Dec 7.
2010
Modifying Akt signaling in B-cell chronic lymphocytic leukemia cells.
Hofbauer SW, Piñón JD, Brachtl G, Haginger L, Wang W, Jöhrer K, Tinhofer I, Hartmann TN, and Greil R.
Cancer Research. 2010 Sep 7. [Epub ahead of print]
2010
Identification of differential and functionally active miRNAs in both anaplastic lymphoma kinase (ALK)+ and ALK- anaplastic large-cell lymphoma.
Merkel O, Hamacher F, Laimer D, Sifft E, Trajanoski Z, Scheideler M, Egger G, Hassler MR, Thallinger C, Schmatz A, Turner SD, Greil R, Kenner L.
Proceedings of the National Academy of Sciences of the United States of America. 2010 Aug 30.
2010
Neue Therapie in Sicht.
Merkel O, Kenner L, Greil R
SpringerMedizin. 22.09.2010
2010
PKCbeta is essential for the development of chronic lymphocytic leukemia in the TCL1 transgenic mouse model: validation of PKCbeta as a therapeutic target in chronic lymphocytic leukemia.
Holler C, Piñón JD, Denk U, Heyder C, Hofbauer S, Greil R, Egle A.
Blood. 2009 Mar 19;113(12):2791-4. Epub 2009 Jan 23.
2009
Circulating B-cell chronic lymphocytic leukemia cells display impaired migration to lymphnodes and bone marrow.
Hartmann T, Grabovsky V, Wang W, Desch P, Rubenzer G, Wollner S, Binsky I, Vallon-Eberhard A, Sapoznikov A, Haran M, Shachar I, Burger M, Honczarenko M, Greil R, Alon R.
Cancer Research. 2009 Apr 1;69(7):3121-30. Epub 2009 Mar 17.
2009
The molecular and cellular biology of chronic lymphocytic leukemia as the basis for novel therapeutic approaches.
Pleyer L, Egle A, Hartmann TN, Greil R.
Nature Clinical Practice Oncology. 2009 Jul;6(7):405-18. Epub 2009 Jun 2. Review.
2009
Difference in the relative distribution of CD4+ T-cell subsets in B-CLL with mutated and unmutated immunoglobulin (Ig) VH genes: implication for the course of disease.
Tinhofer I, Weiss L, Gassner F, Rubenzer G, Holler C, Greil R.
Journal of Immunotherapy. 2009 Apr;32(3):302-9.
2009
Novel therapeutics approaches to chronic lymphocytic leukemia based on recent biological insights.
Hartmann TN, Pleyer L, Desch P, Egle A, Greil R.
Discovering Medicine. 2009 Oct;8(42):157-64. Review.
2009
SNP309 as predictor for sensitivity of CLL cells to the MDM2 inhibitor nutlin-3a.
Seyfried I, Hofbauer S, Stoecher M, Greil R, Tinhofer I.
Blood. 2008 Sep 1;112(5):2168; author reply 2169. No abstract available.
2008
MDM2 SNP309 is associated with poor outcome in B-cell chronic lymphocytic leukemia.
Gryshchenko I, Hofbauer S, Stoecher M, Daniel PT, Steurer M, Gaiger A, Eichenberger K, Greil R, Tinhofer I.
Journal of Clinical Oncology. 2008 May 10; 26(14):2252-7.
2008
Arsenic Trioxide induces apoptosis preferably in B-CLL cells of high risk patients including del17p13.
Merkel O, Heyder C, Asslaber D, Hamacher H, Holler C, Stöcher M, Tinhofer I, Greil R.
Journal of Molecular Medicine-JMM. 2008 May;86(5):541-52. Epub 2008 Feb 23.
2008
Tumour-immune cell interactions modulated by chemokines.
Jöhrer K, Pleyer L, Olivier A, Maizner E, Zelle-Rieser C, Greil R.
Expert Opinion on Biological Therapy. 2008 Mar;8(3):269-90. Review.
2008
The effect of IgVH mutational status on the induction of apoptosis by rituximab in patients with heavily pretreated B-cell chronic lymphocytic leukemia: evidence from a clinical phase I/II trial.
Tinhofer I, Steurer M, Leitinger G, Rumpold H, Egle A, Erdel M, Greil R.
Haematologica-The Hematology Journal. 2006 Sep;91(9):1291-3.
2006
Expression levels of CD38 in T cells predict course of disease in male patients with B-chronic lymphocytic leukemia.
Tinhofer I, Rubenzer G, Holler C, Hofstaetter E, Stoecher M, Egle A, Steurer M, Greil R.
Blood. 2006 Nov 1;108(9):2950-6. Epub 2006 Jul 6.
2006
IL-4 inhibits the TNF-alpha induced proliferation of renal cell carcinoma (RCC) and cooperates with TNF-alpha to induce apoptotic and cytokine responses by RCC: implications for antitumor immune responses.
Falkensammer C, Jöhrer K, Gander H, Ramoner R, Putz T, Rahm A, Greil R, Bartsch G, Thurnher M.
Cancer Immunology Immunotherapy. 2006 Oct;55(10):1228-37. Epub 2006 Jan 28.
2006
A role of TRAIL in killing osteoblasts by myeloma cells.
Tinhofer I, Biedermann R, Krismer M, Crazzolara R, Greil R.
FASEB Journal. 2006 Apr;20(6):759-61. Epub 2006 Jan 25.
2006
Polyacetylenes from the Apiaceae Vegetables Carrot, Celery, Fennel, Parsley, and Parsnip and Their Cytotoxic Activities.
Zidorn C, Johrer K, Ganzera M, Schubert B, Sigmund EM, Mader J, Greil R, Ellmerer EP, Stuppner H.
Journal of Agricultural and Food Chemistry. 2005 Apr 6;53(7):2518-2523.
2005
1,10-Epoxyhypocretenolides from the Azorean Endemic Leontodon rigens (Asteraceae)
Zidorn C, Ellmerer EP, Konwalinka G, Ongania KH, Schwaha R, Greil R, Jöhrer K, Perry NB, Stuppner H
Letters in Organic Chemistry. Volume 2, Number 5, August 2005 , pp. 461-464(4).
2005
Up-regulation of functional chemokine receptor CCR3 in human renal cell carcinoma.
Jöhrer K, Zelle-Rieser C, Perathoner A, Moser P, Hager M, Ramoner R, Gander H, Höltl L, Bartsch G, Greil R, Thurnher M.
Clinical Cancer Research. 2005 Apr 1;11(7):2459-65.
2005
Transendothelial migration of myeloma cells is increased by tumor necrosis factor (TNF)-alpha via TNF receptor 2 and autocrine up-regulation of MCP-1.
Jöhrer K, Janke K, Krugmann J, Fiegl M, Greil R.
Clinical Cancer Research. 2004 Mar 15;10(6):1901-10.
2004
Elevated levels of soluble CD44 are associated with advanced disease and in vitro proliferation of neoplastic lymphocytes in B-cell chronic lymphocytic leukaemia.
Eisterer W, Bechter O, Söderberg O, Nilsson K, Terol M, Greil R, Thaler J, Herold M, Finke L, Günthert U, Montserrat E, Stauder R.
Leukemia Research. 2004 Oct;28(10):1043-51.
2004
Tetrocarcin-A-induced ER stress mediates apoptosis in B-CLL cells via a Bcl-2--independent pathway.
Anether G, Tinhofer I, Senfter M, Greil R.
Blood. 2003 Jun 1;101(11):4561-8. Epub 2003 Jan 30.
2003
Tracking death dealing by Fas and TRAIL in lymphatic neoplastic disorders: pathways, targets, and therapeutic tools.
Greil R, Anether G, Johrer K, Tinhofer I.
Journal of Leukocyte Biology. 2003 Sep;74(3):311-30. Review.
2003
Tuning the rheostat of the myelopoietic system via Fas and TRAIL.
Greil R, Anether G, Johrer K, Tinhofer I.
Critical Reviews in Immunology. 2003;23(4):301-22. Review.
2003
Stressful death of T-ALL tumor cells after treatment with the anti-tumor agent Tetrocarcin-A.
Tinhofer I, Anether G, Senfter M, Pfaller K, Bernhard D, Hara M, Greil R.
FASEB J. 2002 Aug;16(10):1295-7. Epub 2002 Jun 7.
2002
Histone deacetylase inhibitors potently repress CXCR4 chemokine receptor expression and function in acute lymphoblastic leukaemia.
Crazzolara R, Jöhrer K, Johnstone RW, Greil R, Kofler R, Meister B, Bernhard D.
Br J Haematol. 2002 Dec;119(4):965-9.
2002
Interleukin-15 as a potential costimulatory cytokine in CD154 gene therapy of chronic lymphocytic leukemia.
Anether G, Marschitz I, Tinhofer I, Greil R.
Blood, 2002 Jan 15;99(2):722-3.
2002
Resveratrol, a tumor-suppressive compound from grapes, induces apoptosis via a novel mitochondrial pathway controlled by bcl-2.
Tinhofer I, Bernhard D, Senfter M, Anether G, Loeffler M, Kroemer G, Kofler R, Csordas A, Greil R
THE FASEB JOURNAL, 2001 Jul;15(9):1613-5
2001
Inhibition of histone deacetylase activity enhances Fas receptor-mediated apoptosis in leukemic lymphoblasts.
Bernhard D, Skvortsov S, Tinhofer I, Hübl H, Greil R, Csordas A, Kofler R.
Cell Death Differ. 2001 Oct;8(10):1014-21.
2001
Analysis of Bcl-2 protein expression in chronic lymphocytic leukemia: a comparison of three semiquantitation techniques
Marschitz I, Tinhofer I, Hittmair A, Egle A, Kos M, Greil R
AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 113,219-229, 2000
2000
Expression of functional Interleukin-15 receptor and autocrine production of interleukin-15 as mechanisms of tumor propagation in multiple myeloma.
Tinhofer I, Marschitz I, Henn T, Egle A, Greil R
Blood, 2000 Jan 15;95(2):610-618.
2000
Gastric cancer cell lines lack Fas Ligand (FasL) expression but kill T cells via a FasL-independent pathway.
Tinhofer I, Wykypiel H, Marschitz I, Henn T, Greil R.
GUT, 2000 May;46(5):738-740.
2000
Resveratrol causes arrest in the S-phase prior to Fas-independent apoptosis in CEM-C7H2 acute leukemia cells.
Bernhard D, Tinhofer I, Tonko M, Hübl H, Ausserlechner MJ, Greil R, Kofler R, Csordas A.
Cell Death Differ. 2000 Sep;7(9):834-42.
2000
Differential sensitivity of CD4+ and CD8+ T lymphocytes to the killing efficacy of Fas(Apo-1/CD95) ligand+ tumor cells in B chronic lymphocytic leukemia.
Tinhofer I, Marschitz I, Egle A, Henn T, Villunger A, Greil R.
Blood. 1998 Jun 1;91(11):4273-81.
1998
IL-10 serum levels in B-cell chronic lymphocytic leukaemia.
Egle A, Marschitz I, Posch B, Herold M, Greil R.
Br J Haematol. 1996 Jul;94(1):211-2.
1996
Modulation of Apo-1/Fas (CD95)-induced programmed cell death in myeloma cells by interferon-alpha 2.
Egle A, Villunger A, Kos M, Böck G, Gruber J, Auer B, Greil R.
Eur J Immunol. 1996 Dec;26(12):3119-26.
1996
Hartmann T.
Canonical and Noncanonical Hedgehog/GLI Signaling in Hematological Malignancies.
Aberger F, Kern D, Greil R, Hartmann TN.
Vitamins & Hormones. 2012;88:25-54.
01.03.2012
Chemokine-dependent B cell-T cell interactions in chronic lymphocytic leukemia and multiple myeloma - targets for therapeutic intervention?
Jöhrer K, Hofbauer SW, Zelle-Rieser C, Greil R, Hartmann TN.
Expert Opinion on Biological Therapy. 2012 Feb 15.
15.02.2012
Differential Bone Marrow Homing Capacity of VLA-4 and CD38 High Expressing Chronic Lymphocytic Leukemia Cells
Brachtl G, Sahakyan K, Denk U, Girbl T, Alinger B, Hofbauer SW, Neureiter D, Hofbauer JP, Egle A, Greil R, Hartmann TN.
PLoS One. 2011;6(8):e23758. Epub 2011 Aug 18.
18.08.2011
Fludarabine modulates composition and function of the T cell pool in patients with chronic lymphocytic leukaemia.
Gassner FJ, Weiss L, Geisberger R, Hofbauer JP, Egle A, Hartmann TN, Greil R, Tinhofer I.
Cancer Immunol Immunother. 2011 Jan;60(1):75-85. Epub 2010 Sep 21.
01/2011
Inhibition of GLI, but not Smoothened, induces apoptosis in chronic lymphocytic leukemia cells.
Desch P, Asslaber D, Kern D, Schnidar H, Mangelberger D, Alinger B, Stoecher M, Hofbauer SW, Neureiter D, Tinhofer I, Aberger F, Hartmann TN, Greil R.
Oncogene. 2010 Sep 2;29(35):4885-95. Epub 2010 Jul 5.
02.09.2010
Erforschung der Chronisch Lymphatischen Leukämie am LIMCR.
Hartmann TN.
Med.ium. 6/2010.
06/2010
ÖGHO-Frühjahrstagung: Chronische Lymphatische Leukämie, Adhäsionsmoleküle als mögliche therapeutische Ziele.
Hartmann TN.
JATROS Haematologie und Onkologie. 3/2010, Seite 63-65.
03/2010
Modifying Akt signaling in B-cell chronic lymphocytic leukemia cells.
Hofbauer SW, Piñón JD, Brachtl G, Haginger L, Wang W, Jöhrer K, Tinhofer I, Hartmann TN, and Greil R.
Cancer Research. 2010 Sep 7. [Epub ahead of print]
2010
CCL19 is a specific ligand of the constitutively recycling atypical human chemokine receptor CRAM-B.
Leick M, Catusse J, Follo M, Nibbs RJ, Hartmann TN, Veelken H, Burger M.
Immunology. 2010 Apr;129(4):536-46. Epub 2009 Dec 2.
2010
Circulating B-cell chronic lymphocytic leukemia cells display impaired migration to lymphnodes and bone marrow.
Hartmann T, Grabovsky V, Wang W, Desch P, Rubenzer G, Wollner S, Binsky I, Vallon-Eberhard A, Sapoznikov A, Haran M, Shachar I, Burger M, Honczarenko M, Greil R, Alon R.
Cancer Research. 2009 Apr 1;69(7):3121-30. Epub 2009 Mar 17.
2009
The molecular and cellular biology of chronic lymphocytic leukemia as the basis for novel therapeutic approaches.
Pleyer L, Egle A, Hartmann TN, Greil R.
Nature Clinical Practice Oncology. 2009 Jul;6(7):405-18. Epub 2009 Jun 2. Review.
2009
Novel therapeutics approaches to chronic lymphocytic leukemia based on recent biological insights.
Hartmann TN, Pleyer L, Desch P, Egle A, Greil R.
Discovering Medicine. 2009 Oct;8(42):157-64. Review.
2009
A crosstalk between intracellular CXCR7 and CXCR4 involved in rapid CXCL12-triggered integrin activation but not integrin activation but not in chemokine-triggered motility of human T lymphocytes and CD34+ cells.
Hartmann TN, Grabovsky V, Pasvolsky R, Shulman Z, Buss EC, Spiegel A, Nagler A, Lapidot T, Thelen M, Alon R.
Journal of Leukocyte Biology. 2008 Oct; 84(4): 1130-40.
2008
Canonical and Noncanonical Hedgehog/GLI Signaling in Hematological Malignancies.
Aberger F, Kern D, Greil R, Hartmann TN.
Vitamins & Hormones. 2012;88:25-54.
01.03.2012
Chemokine-dependent B cell-T cell interactions in chronic lymphocytic leukemia and multiple myeloma - targets for therapeutic intervention?
Jöhrer K, Hofbauer SW, Zelle-Rieser C, Greil R, Hartmann TN.
Expert Opinion on Biological Therapy. 2012 Feb 15.
15.02.2012
Differential Bone Marrow Homing Capacity of VLA-4 and CD38 High Expressing Chronic Lymphocytic Leukemia Cells
Brachtl G, Sahakyan K, Denk U, Girbl T, Alinger B, Hofbauer SW, Neureiter D, Hofbauer JP, Egle A, Greil R, Hartmann TN.
PLoS One. 2011;6(8):e23758. Epub 2011 Aug 18.
18.08.2011
Fludarabine modulates composition and function of the T cell pool in patients with chronic lymphocytic leukaemia.
Gassner FJ, Weiss L, Geisberger R, Hofbauer JP, Egle A, Hartmann TN, Greil R, Tinhofer I.
Cancer Immunol Immunother. 2011 Jan;60(1):75-85. Epub 2010 Sep 21.
01/2011
Inhibition of GLI, but not Smoothened, induces apoptosis in chronic lymphocytic leukemia cells.
Desch P, Asslaber D, Kern D, Schnidar H, Mangelberger D, Alinger B, Stoecher M, Hofbauer SW, Neureiter D, Tinhofer I, Aberger F, Hartmann TN, Greil R.
Oncogene. 2010 Sep 2;29(35):4885-95. Epub 2010 Jul 5.
02.09.2010
Erforschung der Chronisch Lymphatischen Leukämie am LIMCR.
Hartmann TN.
Med.ium. 6/2010.
06/2010
ÖGHO-Frühjahrstagung: Chronische Lymphatische Leukämie, Adhäsionsmoleküle als mögliche therapeutische Ziele.
Hartmann TN.
JATROS Haematologie und Onkologie. 3/2010, Seite 63-65.
03/2010
Modifying Akt signaling in B-cell chronic lymphocytic leukemia cells.
Hofbauer SW, Piñón JD, Brachtl G, Haginger L, Wang W, Jöhrer K, Tinhofer I, Hartmann TN, and Greil R.
Cancer Research. 2010 Sep 7. [Epub ahead of print]
2010
CCL19 is a specific ligand of the constitutively recycling atypical human chemokine receptor CRAM-B.
Leick M, Catusse J, Follo M, Nibbs RJ, Hartmann TN, Veelken H, Burger M.
Immunology. 2010 Apr;129(4):536-46. Epub 2009 Dec 2.
2010
Circulating B-cell chronic lymphocytic leukemia cells display impaired migration to lymphnodes and bone marrow.
Hartmann T, Grabovsky V, Wang W, Desch P, Rubenzer G, Wollner S, Binsky I, Vallon-Eberhard A, Sapoznikov A, Haran M, Shachar I, Burger M, Honczarenko M, Greil R, Alon R.
Cancer Research. 2009 Apr 1;69(7):3121-30. Epub 2009 Mar 17.
2009
The molecular and cellular biology of chronic lymphocytic leukemia as the basis for novel therapeutic approaches.
Pleyer L, Egle A, Hartmann TN, Greil R.
Nature Clinical Practice Oncology. 2009 Jul;6(7):405-18. Epub 2009 Jun 2. Review.
2009
Novel therapeutics approaches to chronic lymphocytic leukemia based on recent biological insights.
Hartmann TN, Pleyer L, Desch P, Egle A, Greil R.
Discovering Medicine. 2009 Oct;8(42):157-64. Review.
2009
A crosstalk between intracellular CXCR7 and CXCR4 involved in rapid CXCL12-triggered integrin activation but not integrin activation but not in chemokine-triggered motility of human T lymphocytes and CD34+ cells.
Hartmann TN, Grabovsky V, Pasvolsky R, Shulman Z, Buss EC, Spiegel A, Nagler A, Lapidot T, Thelen M, Alon R.
Journal of Leukocyte Biology. 2008 Oct; 84(4): 1130-40.
2008
Hopfinger G.
ASH Report. Novel agents in diffuse large B-cell lymphoma: A short update including ASH 2010.
Melchardt T, Hofbauer SW, Greil R, Hopfinger G.
Memo - Magazine of European Medical Oncology. 2011 June 1; 4(2): 120-123.
01.06.2011
Melchardt T.
ASH Report. Novel agents in diffuse large B-cell lymphoma: A short update including ASH 2010.
Melchardt T, Hofbauer SW, Greil R, Hopfinger G.
Memo - Magazine of European Medical Oncology. 2011 June 1; 4(2): 120-123.
01.06.2011
Regulatory T cells predict the time to initial treatment in early stage chronic lymphocytic leukemia.
Weiss L, Melchardt T, Egle A, Grabmer C, Greil R, Tinhofer I.
Cancer. 2011 May 15;117(10):2163-9. doi: 10.1002/cncr.25752. Epub 2010 Nov 18
15.05.2011
An uncommon cause of anaemia: Sheehan's syndrome.
Melchardt T, Namberger K, Weiss L, Egle A, Faber V, Greil R.
Wiener Klinische Wochenschrift. 2010 Dec 7.
2010
ASH Report. Novel agents in diffuse large B-cell lymphoma: A short update including ASH 2010.
Melchardt T, Hofbauer SW, Greil R, Hopfinger G.
Memo - Magazine of European Medical Oncology. 2011 June 1; 4(2): 120-123.
01.06.2011
Regulatory T cells predict the time to initial treatment in early stage chronic lymphocytic leukemia.
Weiss L, Melchardt T, Egle A, Grabmer C, Greil R, Tinhofer I.
Cancer. 2011 May 15;117(10):2163-9. doi: 10.1002/cncr.25752. Epub 2010 Nov 18
15.05.2011
An uncommon cause of anaemia: Sheehan's syndrome.
Melchardt T, Namberger K, Weiss L, Egle A, Faber V, Greil R.
Wiener Klinische Wochenschrift. 2010 Dec 7.
2010
Merkel O.
Antimyeloma activity of the sesquiterpene lactone cnicin: impact on Pim-2 kinase as a novel therapeutic target.
Jöhrer K, Obkircher M, Neureiter D, Parteli J, Zelle-Rieser C, Maizner E, Kern J, Hermann M, Hamacher F, Merkel O, Wacht N, Zidorn C, Scheideler M, Greil R.
Journal of Molecular Medicine-JMM. 2011 Dec 29.
29.12.2011
Anaplastic large cell lymphoma: the current state of play from a European prospective as presented at the second annual meeting of the European Research Initiative on ALCL, 27-28 June 2011.
Merkel O, Kenner L, Turner SD.
Leukemia. Dec;25(12):1795-6. doi: 10.1038/leu.2011.295.
12/2011
Novel Therapeutic Options in Anaplastic Large Cell Lymphoma: Molecular Targets and Immunological Tools.
Merkel O, Hamacher F, Sifft E, Kenner L, Greil R; for the European Research Initiative on Anaplastic Large Cell Lymphoma.
Molecular Cancer Therapeutics. 2011 Jun 28.
28.06.2011
microRNA-34a expression correlates with MDM2 SNP309 polymorphism and treatment-free survival in chronic lymphocytic leukemia.
Asslaber D, Piñón JD, Seyfried I, Desch P, Stöcher M, Tinhofer I, Egle A, Merkel O, Greil R.
Blood. 2010 May 27;115(21):4191-7. Epub 2010 Jan 20.
27.05.2010
Interdependent regulation of p53 and miR-34a in chronic lymphocytic leukemia.
Merkel O, Asslaber D, Piñón JD, Egle A, Greil R.
Cell Cycle. 2010 Jul 15;9(14):2764-8. Epub 2010 Jul 3.
2010
Identification of differential and functionally active miRNAs in both anaplastic lymphoma kinase (ALK)+ and ALK- anaplastic large-cell lymphoma.
Merkel O, Hamacher F, Laimer D, Sifft E, Trajanoski Z, Scheideler M, Egger G, Hassler MR, Thallinger C, Schmatz A, Turner SD, Greil R, Kenner L.
Proceedings of the National Academy of Sciences of the United States of America. 2010 Aug 30.
2010
Neue Therapie in Sicht.
Merkel O, Kenner L, Greil R
SpringerMedizin. 22.09.2010
2010
Arsenic Trioxide induces apoptosis preferably in B-CLL cells of high risk patients including del17p13.
Merkel O, Heyder C, Asslaber D, Hamacher H, Holler C, Stöcher M, Tinhofer I, Greil R.
Journal of Molecular Medicine-JMM. 2008 May;86(5):541-52. Epub 2008 Feb 23.
2008
Mitochondrial phosphate-carrier deficiency: a novel disorder of oxidative phosphorylation.
Mayr JA, Merkel O, Kohlwein SD, Gebhardt BR, Böhles H, Fötschl U, Koch J, Jaksch M, Lochmüller H, Horvath R, Freisinger P, Sperl W.
American Journal of Human Genetics. 2007 Mar;80(3):478-84. Epub 2007 Jan 10.
2007
Antimyeloma activity of the sesquiterpene lactone cnicin: impact on Pim-2 kinase as a novel therapeutic target.
Jöhrer K, Obkircher M, Neureiter D, Parteli J, Zelle-Rieser C, Maizner E, Kern J, Hermann M, Hamacher F, Merkel O, Wacht N, Zidorn C, Scheideler M, Greil R.
Journal of Molecular Medicine-JMM. 2011 Dec 29.
29.12.2011
Anaplastic large cell lymphoma: the current state of play from a European prospective as presented at the second annual meeting of the European Research Initiative on ALCL, 27-28 June 2011.
Merkel O, Kenner L, Turner SD.
Leukemia. Dec;25(12):1795-6. doi: 10.1038/leu.2011.295.
12/2011
Novel Therapeutic Options in Anaplastic Large Cell Lymphoma: Molecular Targets and Immunological Tools.
Merkel O, Hamacher F, Sifft E, Kenner L, Greil R; for the European Research Initiative on Anaplastic Large Cell Lymphoma.
Molecular Cancer Therapeutics. 2011 Jun 28.
28.06.2011
microRNA-34a expression correlates with MDM2 SNP309 polymorphism and treatment-free survival in chronic lymphocytic leukemia.
Asslaber D, Piñón JD, Seyfried I, Desch P, Stöcher M, Tinhofer I, Egle A, Merkel O, Greil R.
Blood. 2010 May 27;115(21):4191-7. Epub 2010 Jan 20.
27.05.2010
Interdependent regulation of p53 and miR-34a in chronic lymphocytic leukemia.
Merkel O, Asslaber D, Piñón JD, Egle A, Greil R.
Cell Cycle. 2010 Jul 15;9(14):2764-8. Epub 2010 Jul 3.
2010
Identification of differential and functionally active miRNAs in both anaplastic lymphoma kinase (ALK)+ and ALK- anaplastic large-cell lymphoma.
Merkel O, Hamacher F, Laimer D, Sifft E, Trajanoski Z, Scheideler M, Egger G, Hassler MR, Thallinger C, Schmatz A, Turner SD, Greil R, Kenner L.
Proceedings of the National Academy of Sciences of the United States of America. 2010 Aug 30.
2010
Neue Therapie in Sicht.
Merkel O, Kenner L, Greil R
SpringerMedizin. 22.09.2010
2010
Arsenic Trioxide induces apoptosis preferably in B-CLL cells of high risk patients including del17p13.
Merkel O, Heyder C, Asslaber D, Hamacher H, Holler C, Stöcher M, Tinhofer I, Greil R.
Journal of Molecular Medicine-JMM. 2008 May;86(5):541-52. Epub 2008 Feb 23.
2008
Mitochondrial phosphate-carrier deficiency: a novel disorder of oxidative phosphorylation.
Mayr JA, Merkel O, Kohlwein SD, Gebhardt BR, Böhles H, Fötschl U, Koch J, Jaksch M, Lochmüller H, Horvath R, Freisinger P, Sperl W.
American Journal of Human Genetics. 2007 Mar;80(3):478-84. Epub 2007 Jan 10.
2007
Namberger K.
An uncommon cause of anaemia: Sheehan's syndrome.
Melchardt T, Namberger K, Weiss L, Egle A, Faber V, Greil R.
Wiener Klinische Wochenschrift. 2010 Dec 7.
2010
Pleyer L.
The molecular and cellular biology of chronic lymphocytic leukemia as the basis for novel therapeutic approaches.
Pleyer L, Egle A, Hartmann TN, Greil R.
Nature Clinical Practice Oncology. 2009 Jul;6(7):405-18. Epub 2009 Jun 2. Review.
2009
Novel therapeutics approaches to chronic lymphocytic leukemia based on recent biological insights.
Hartmann TN, Pleyer L, Desch P, Egle A, Greil R.
Discovering Medicine. 2009 Oct;8(42):157-64. Review.
2009
Tumour-immune cell interactions modulated by chemokines.
Jöhrer K, Pleyer L, Olivier A, Maizner E, Zelle-Rieser C, Greil R.
Expert Opinion on Biological Therapy. 2008 Mar;8(3):269-90. Review.
2008
Stöcher M.
microRNA-34a expression correlates with MDM2 SNP309 polymorphism and treatment-free survival in chronic lymphocytic leukemia.
Asslaber D, Piñón JD, Seyfried I, Desch P, Stöcher M, Tinhofer I, Egle A, Merkel O, Greil R.
Blood. 2010 May 27;115(21):4191-7. Epub 2010 Jan 20.
27.05.2010
Arsenic Trioxide induces apoptosis preferably in B-CLL cells of high risk patients including del17p13.
Merkel O, Heyder C, Asslaber D, Hamacher H, Holler C, Stöcher M, Tinhofer I, Greil R.
Journal of Molecular Medicine-JMM. 2008 May;86(5):541-52. Epub 2008 Feb 23.
2008
microRNA-34a expression correlates with MDM2 SNP309 polymorphism and treatment-free survival in chronic lymphocytic leukemia.
Asslaber D, Piñón JD, Seyfried I, Desch P, Stöcher M, Tinhofer I, Egle A, Merkel O, Greil R.
Blood. 2010 May 27;115(21):4191-7. Epub 2010 Jan 20.
27.05.2010
Arsenic Trioxide induces apoptosis preferably in B-CLL cells of high risk patients including del17p13.
Merkel O, Heyder C, Asslaber D, Hamacher H, Holler C, Stöcher M, Tinhofer I, Greil R.
Journal of Molecular Medicine-JMM. 2008 May;86(5):541-52. Epub 2008 Feb 23.
2008
Weiss L.
Regulatory T cells predict the time to initial treatment in early stage chronic lymphocytic leukemia.
Weiss L, Melchardt T, Egle A, Grabmer C, Greil R, Tinhofer I.
Cancer. 2011 May 15;117(10):2163-9. doi: 10.1002/cncr.25752. Epub 2010 Nov 18
15.05.2011
Fludarabine modulates composition and function of the T cell pool in patients with chronic lymphocytic leukaemia.
Gassner FJ, Weiss L, Geisberger R, Hofbauer JP, Egle A, Hartmann TN, Greil R, Tinhofer I.
Cancer Immunol Immunother. 2011 Jan;60(1):75-85. Epub 2010 Sep 21.
01/2011
An uncommon cause of anaemia: Sheehan's syndrome.
Melchardt T, Namberger K, Weiss L, Egle A, Faber V, Greil R.
Wiener Klinische Wochenschrift. 2010 Dec 7.
2010
Difference in the relative distribution of CD4+ T-cell subsets in B-CLL with mutated and unmutated immunoglobulin (Ig) VH genes: implication for the course of disease.
Tinhofer I, Weiss L, Gassner F, Rubenzer G, Holler C, Greil R.
Journal of Immunotherapy. 2009 Apr;32(3):302-9.
2009
Regulatory T cells predict the time to initial treatment in early stage chronic lymphocytic leukemia.
Weiss L, Melchardt T, Egle A, Grabmer C, Greil R, Tinhofer I.
Cancer. 2011 May 15;117(10):2163-9. doi: 10.1002/cncr.25752. Epub 2010 Nov 18
15.05.2011
Fludarabine modulates composition and function of the T cell pool in patients with chronic lymphocytic leukaemia.
Gassner FJ, Weiss L, Geisberger R, Hofbauer JP, Egle A, Hartmann TN, Greil R, Tinhofer I.
Cancer Immunol Immunother. 2011 Jan;60(1):75-85. Epub 2010 Sep 21.
01/2011
An uncommon cause of anaemia: Sheehan's syndrome.
Melchardt T, Namberger K, Weiss L, Egle A, Faber V, Greil R.
Wiener Klinische Wochenschrift. 2010 Dec 7.
2010
Difference in the relative distribution of CD4+ T-cell subsets in B-CLL with mutated and unmutated immunoglobulin (Ig) VH genes: implication for the course of disease.
Tinhofer I, Weiss L, Gassner F, Rubenzer G, Holler C, Greil R.
Journal of Immunotherapy. 2009 Apr;32(3):302-9.
2009